Anti- integrin antibodies, compositions, methods and uses
OwnerJill Giles-Komar, Linda Snyder +2inventors
InventorsJill Giles-Komar, Linda Snyder, Mohit Trikha, Marian T. Nakada
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Abstract
The present invention relates to at least one novel anti-alpha-V subunit antibodies, including isolated nucleic acids that encode at least one anti-alpha-V subunit antibody, alpha-V subunit, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
Claims20
A method for modulating angiogenesis in a cell, tissue, organ or animal, comprising administering a composition comprising an effective amount of an isolated human anti-αV subunit antibody or antigen-binding fragment thereof, to said cell, tissue, organ or animal
A method for inhibiting microcapillary formation in a cell, tissue, organ or animal, comprising administering a composition comprising an effective amount of an isolated human anti-αV subunit antibody or antigen-binding fragment thereof, to said cell, tissue, organ or animal.
A method for treating malignant disease in an animal in need thereof, comprising administering a composition comprising an effective amount of an isolated human anti-αV subunit antibody or antigen-binding fragment thereof, to said cell, tissue, organ or animal
Dependencies are inferred from the claim text.