Influenza virus-neutralizing antibody and screening method therefor
AssigneesThe Research Foundation for Microbial Diseases of Osaka University, Fujita Health University
InventorsYoshikazu KUROSAWA, Yoshitaka IBA, Nobuko OHSHIMA, Yoshinobu OKUNO
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Abstract
Provided is an anti-influenza virus antibody that exhibits neutralizing activity beyond the barrier of the two groups of influenza viruses categorized according to the conservativeness of hemagglutinin amino acids, a method of producing the same, and a test method for determining whether the subject carries the neutralizing antibody.
Claims30
An isolated antibody that neutralizes both at least one influenza virus selected from Group 1 consisting of subtype H1, subtype H2, subtype H5, subtype H6, subtype H8, subtype H9, subtype H11, subtype H12, subtype H13 and subtype H16 influenza viruses and at least one influenza virus selected from Group 2 consisting of subtype H3, subtype H4, subtype H7, subtype H10, subtype H14 and subtype H15 influenza viruses.
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