Sialylated antigen-specific antibodies for treatment or prophylaxis of unwanted inflammatory immune reactions and methods of producing them
OwnerMarc Ehlers, Constanze Hess +2inventors
InventorsMarc Ehlers, Constanze Hess, Alexandra Katharina Lorenz, André Winkler
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Abstract
The present invention is directed to a sialylated isolated antibody specific for an antigen selected from autoimmune antigens, allergens, MHC molecules or Rhesus factor D antigen, comprising an Fc-portion of IgG type, and exhibiting a sialic acid residue at the Fc-portion for use in treatment and/or prophylaxis of autoimmune disease, allergy, transplant rejection or Rhesus factor D reactivity and to methods of producing such an antibody.
Claims13
1-15. (canceled)
Sialylated isolated antibody specific for an antigen selected from autoimmune antigens, allergens, MHC molecules or Rhesus factor D antigen, comprising an Fc-portion of IgG type, and exhibiting a sialic acid residue at the Fc-portion for use in treatment and/or prophylaxis of autoimmune disease, allergy, transplant rejection or Rhesus factor D reactivity.
Pharmaceutical composition comprising an antibody according to claim 1 and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.