7-Nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or derivatives thereof for treating or preventing antiviral infections
OwnerShaikh Riazuddin, Atta-ur Rehman +7inventors
InventorsShaikh Riazuddin, Atta-ur Rehman, Usman Zafar, Iqbal Choudhary, Usman Ali Ashfaq, Khalid M. Khan, Tayyab Husnain, Zulfiqar Ali Khan, Javed Akram
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Abstract
Surprising antiviral activity of 7-Nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one (Compound 1) was reported in the treatment or prevention of viral infections, particularly in combination with other antiviral agents such as interferon and/or ribavarin.
Claims5
A method for the treatment of hepatitis C virus infection in a host, comprising contacting a cell infected with a hepatitis C virus an effective amount of 7-Nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or a pharmaceutically acceptable salt or ester thereof.
A pharmaceutical composition comprising a compound 7-Nitro-2-(3-nitro phenyl)-4H-3,1-benzoxazin-4-one or a pharmaceutically acceptable salt or ester thereof, in combination with one or more other antiviral agents, and one or more pharmaceutically acceptable carriers, excipients or diluents.
Dependencies are inferred from the claim text.