Self-assembling peptide and peptide gel with high strength
AssigneesNational Univ. Corporation Okayama Univ., Menicon Co., Ltd.
InventorsYusuke Nagai, Hidenori Yokoi, Koji Uesugi, Keiji Naruse
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Abstract
Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following amino acid sequence: a1b1c1b2a2b3db4a3b5c2b6a4 where: a1 to a4 each represent a basic amino acid residue; b1 to b6 each represent an uncharged polar amino acid residue and/or a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue; c1 and c2 each represent an acidic amino acid residue; and d represents a hydrophobic amino acid residue.
Claims20
A self-assembling peptide, comprising an amino acid sequence:
- a1b1c1b2a2b3db4a3b5c2b6a4,
- wherein a1 to a4 each represent a basic amino acid residue,
- b1 to b6 each represent at least one selected from the group consisting of an uncharged polar amino acid residue and a hydrophobic amino acid residue, provided that at least five thereof each represent a hydrophobic amino acid residue,
- c1 and c2 each represent an acidic amino acid residue, and
- d represents a hydrophobic amino acid residue.
Dependencies are inferred from the claim text.