Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation
OwnerJames H. Silver, Darius F. Mostowfiinventors
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Abstract
A system is disclosed that extracts bodily fluid to a reaction chamber for monitoring a substance or property of the patient fluid. In one embodiment, a pump is used to advance the sample of bodily fluid through a filter to produce a filtrate. Another pump advances filtrate into the reaction chamber, while another pump advances reactant into the reaction chamber. A sensor in communication with the reaction chamber determines a concentration of nitric oxide or one of its metabolic products. Methods are also disclosed.
Claims19
A system for measuring nitric oxide or one of its metabolic products, the system comprising:
- a reaction chamber;
- a fluid flow path extending between an end adapted for receiving a sample of bodily fluid and the reaction chamber;
- a filter in the flow path;
- a pump for advancing the sample through the filter to produce a filtrate and advancing the filtrate into the reaction chamber;
- and
- a sensor in communication with the reaction chamber for determining a concentration of nitric oxide or one of its metabolic products.
A system for measuring nitric oxide or one of its metabolic products, the system comprising:
- a reaction chamber;
- a fluid flow path extending between an end adapted for receiving a sample of bodily fluid and the reaction chamber;
- a filter in the flow path;
- a pump for advancing the sample through the filter to produce a filtrate;
- a first reactant reservoir in communication with the reaction chamber;
- a flow regulator in the flow path;
- and
- a sensor in communication with the reaction chamber for determining a concentration of nitric oxide or one of its metabolic products.
Dependencies are inferred from the claim text.