Polysaccharide pseudo-sponge
AssigneeSeikagaku Corporation
InventorTomoya SATO
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Abstract
A photocrosslinked polysaccharide pseudo-sponge exhibiting a low swelling property and a high degradation ability in vivo while retaining a suitable strength. The polysaccharide pseudo-sponge is produced by a crosslinking reaction of a photoreactive polysaccharide obtained by introducing a photoreactive group into a polysaccharide, and exhibits a low swelling property and a blue dextran-low dyeaffinity.
Claims19
-22. (canceled)
A process for producing a polysaccharide pseudo-sponge, comprising:
- irradiating light to a solution of a photoreactive polysaccharide having a photoreactive group to obtain a polysaccharide gel having a shape-retention property,
- freezing or freeze-drying the obtained polysaccharide gel, and then
- irradiating light to the resultant frozen or freeze-dried polysaccharide gel.
The process according to 23, wherein the polysaccharide is glucan, glycuronan or glycosaminoglycan.
A process for producing a polysaccharide pseudo-sponge, comprising:
- irradiating light to a solution of a photoreactive polysaccharide having a photoreactive group to obtain a polysaccharide gel having a shape-retention property,
- freezing or freeze-drying the obtained polysaccharide gel, and then irradiating light to the resultant frozen or freeze-dried polysaccharide gel,
- wherein the polysaccharide is selected from the group consisting of hyaluronic acid, alginic acid and carboxymethyl cellulose, and
- the photoreactive group is selected from cinnamic acid, substituted cinnamic acid or aminocinnamic acid, acrylic acid, maleic acid, fumaric acid, furyl-acrylic acid, thiophene-acrylic acid, cinnamylidene-acetic acid, sorbic acid, thymine, coumarin, and derivatives thereof.
Dependencies are inferred from the claim text.