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US 2012/0048788 A1Published application
Method and installation for regulating the modifier level in chromatography or supercritical extraction with recycling
AssigneePIC Solution
InventorMohamed Shaimi
Life of this patent
Estimating the term…
Abstract
A chromatography or supercritical extraction method is disclosed, in which the eluent comprises a mixture of a fluid and a modifier and in which the fluid is recycled. One exemplary method comprises an operation consisting in determining at least one quantity linked to the level of modifier that is mixed with the recycled fluid and, if necessary, a correction operation in order to limit variations in the level of modifier in the eluent at the inlet of the column or the extractor. The disclosure also relates to a chromatography or extraction installation.
Claims21
A separation installation comprising:
- a separation device configured to receive a product, an eluent, and a modifier;
- a collection device downstream of said separation device, said collection device configured to collect at least a fraction of said product output from said separation device;
- a recycle path downstream of said collection device, said recycle path configured to recycle at least a portion of said eluent output from said separation device;
- and
- a measuring and correcting device downstream of said collection device and upstream of said separation device, said measuring and correcting device configured to measure at least one magnitude associated with a level of modifier in said recycled eluent and to modify at least one of a flow of said eluent and a flow of said modifier in response to said measurement.
2 more elements
A separation installation comprising:
- a separation device configured to receive a product, a supercritical fluid, and a modifier;
- a collection device downstream of said separation device, said collection device configured to receive an output of said separation device and collect at least a fraction of said product output from said separation device;
- and
- a measuring and correcting device downstream of said collection device and upstream of said separation device, said measuring and correcting device configured to receive a recycled supercritical fluid output from said collection device and modify at least one of a flow of said modifier and a flow of said supercritical fluid to limit variations when said separation installation is running.
1 more element
Dependencies are inferred from the claim text.