# US 2012/0031398 A1 · Nasal spray device

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- Number: US 2012/0031398 A1
- Document ID: US20120031398A1
- Status: Published application
- Kind: A1
- Application number: 13/127,418
- Filed: 2009-11-03
- Published: 2012-02-09
- Earliest claimed: 2008-11-03
- Assignees: Schering Corporation
- Inventors: Robert L. Berger; Michael L. Turini; Peter A. Basile; Stephen Miggels; Henry J. Mack
- Web page: https://patentgrep.com/patent/US20120031398A1

## CPC

- A61M 15/08: Inhaling devices inserted into the nose
- A61M 15/0026: {Hinged caps}
- A61M 15/009: {using medicine packages with incorporated spraying means, e.g. aerosol cans (pocket atomiser of the injector type A61M11/08)}
- B05B 11/1053: {combined with means, other than pressure, for automatically opening a valve during actuation; combined with means for automatically removing closures or covers from the discharge nozzle during actuation}
- B05B 11/1056: {comprising rotatable or articulated levers (B05B11/1053 takes precedence; lever actuated piston pumps B05B11/1009; lever actuated pumps with deformable chamber B05B11/1029)}
- B05B 11/0032: {Manually actuated means located downstream the discharge nozzle for closing or covering it, e.g. shutters (automatically removed during actuation of a spray pump B05B11/1053)}
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- B05B: SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES (spray-mixers with nozzles B01F25/72; processes for applying liquids or other fluent materials to surfaces by spraying B05D)

## Abstract

A delivery device (10) for the delivery of at least one dose of a composition into a nasal cavity, the device has a discharge member (12) formed for insertion into a nasal cavity, a discharge aperture (20) being formed therethrough and a body (14) containing a reservoir (24) of at least one dose, the body is elongated and generally extending along a longitudinal axis (16), wherein the discharge member (12) extends along a secondary axis (18), the secondary axis (18) intersecting with, and being disposed transversely to the longitudinal axis (16).

## Claims

### Claim 1

A delivery device for the delivery of at least one dose of a composition into a nasal cavity, the device comprising:
a discharge member formed for insertion into a nasal cavity, a discharge aperture being formed therethrough; and,
a body containing a reservoir of at least one dose, the body being elongated and generally extending along a longitudinal axis, wherein the discharge member extends along a secondary axis, the secondary axis intersecting with, and being disposed transversely to, the longitudinal axis.

### Claim 2 (depends on 1)

A delivery device as in claim 1, wherein the secondary axis subtends an acute angle with the longitudinal axis.

### Claim 3 (depends on 1)

A delivery device as in claim 1, wherein the secondary axis is generally perpendicular to the longitudinal axis.

### Claim 4 (depends on 1)

A delivery device as in claim 1, further comprising a trigger for causing delivery of at least one dose from the reservoir through the discharge aperture, the trigger being located on the body and spaced from the discharge member.

### Claim 5 (depends on 4)

A delivery device as in claim 4, wherein the trigger is adapted to be actuable with force being applied thereto in a direction transverse to the longitudinal axis.

### Claim 6 (depends on 1)

A delivery device as in claim 1, wherein the discharge member terminates at a free end, the discharge aperture being formed through the free end.

### Claim 7 (depends on 6)

A delivery device as in claim 6, wherein the discharge aperture is formed at the furthestmost location on the discharge member from the body.

### Claim 8 (depends on 1)

A delivery device as in claim 1, wherein the reservoir is elongated and extends along the longitudinal axis.

### Claim 9 (depends on 8)

A delivery device as in claim 8, wherein a portion of the reservoir extends transversely away from the longitudinal axis.

### Claim 10 (depends on 9)

A delivery device as in claim 9, wherein the portion defines a well for collecting the composition gravitationally below the longitudinal axis during use of the delivery device.

### Claim 11 (depends on 10)

A delivery device as in claim 10, further comprising a pump for delivering the at least one dose from the reservoir and through the discharge aperture.

### Claim 12 (depends on 11)

A delivery device as in claim 11, further comprising a dip tube having first and second ends with a lumen extending therebetween, the first end being positioned in a furthermost section of the well from the longitudinal axis, a second end of the dip tube being in communication with the pump, the lumen communicating the well with the pump.

### Claim 13

(canceled)

### Claim 14 (depends on 11)

A delivery device as in claim 11, further comprising a trigger for causing actuation of the pump to cause delivery of the at least one dose from the reservoir through the discharge aperture.

### Claim 15

(canceled)

### Claim 16

(canceled)

### Claim 17

(canceled)

### Claim 18

A delivery device for the delivery of at least one dose of a composition into a nasal cavity, the device comprising:
a discharge member formed for insertion into a nasal cavity, a discharge aperture being formed therethrough;
a stop surface defined at least partially about the discharge member, the stop surface extending radially outwardly from the discharge member, the stop surface limiting the extent the discharge member may be inserted into a nasal cavity; and,
a body containing a reservoir of at least one dose, the body being elongated and generally extending along a longitudinal axis, wherein the discharge member extends along a secondary axis, the secondary axis intersecting with, and being disposed transversely to, the longitudinal axis.

### Claim 19

(canceled)

### Claim 20

(canceled)

### Claim 21

(canceled)

### Claim 22

(canceled)

### Claim 23

(canceled)

### Claim 24

(canceled)

### Claim 25

(canceled)

### Claim 26

(canceled)

### Claim 27

A delivery device for the delivery of at least one dose of composition into a nasal cavity, the device comprising:
a discharge member formed for insertion into a nasal cavity, a discharge aperture being formed therethrough; and,
a body containing a reservoir of at least one dose, the body being elongated and generally extending along a longitudinal axis;
a trigger for causing delivery of at least one dose from the reservoir through the discharge aperture, the trigger being located on the body and spaced from the discharge member;
wherein the discharge member extends along a secondary axis, the secondary axis intersecting with, and being disposed transversely to, the longitudinal axis; and
wherein the trigger is configured to have a force applied thereto for actuation, the force being applied in a direction generally oblique to the longitudinal axis.

### Claim 28 (depends on 27)

A delivery device as in claim 27, wherein the secondary axis subtends an acute angle with the longitudinal axis.

### Claim 29 (depends on 28)

A delivery device as in claim 28, wherein the acute angle is in the range from about 15° to about 45°.

### Claim 30

(canceled)

### Claim 31

(canceled)

### Claim 32

(canceled)

### Claim 33

(canceled)

### Claim 34 (depends on 27)

A delivery device as in claim 27, wherein the trigger is pivotally attached to the body.

### Claim 35 (depends on 27)

A delivery device as in claim 27, wherein the trigger extends along a central axis, the central axis subtends an acute angle with the longitudinal axis.

### Claim 36

(canceled)

### Claim 37

(canceled)

### Claim 38 (depends on 27)

A drug product comprising the device of claim 27 and a composition comprising at least one active pharmaceutical agent.

### Claim 39

(canceled)