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US 2012/0015442 A1Published application
Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
AssigneeCytonome/St, LLC
InventorsJohn Richard Gilbert, Sebastian Böhm, Manish Deshpande
Life of this patent
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Abstract
A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a gas bubble in a liquid in the microchannel when a sufficient pressure is generated on the membrane.
Claims29
1-19. (canceled)
A microfluidic system comprising:
- a microfluidic flow channel formed in a substrate and adapted to facilitate analysis or processing of a sample having one or more particles suspended in a suspension medium flowing through the flow channel;
- a first reservoir operatively associated with the flow channel;
- and
- a second reservoir operatively associated with the flow channel and adapted for dampening or absorbing a pressure pulse resulting from a change in volume or pressure in the first reservoir.
1 more element
A method comprising:
- flowing a sample having one or more particles suspended in a suspension medium through a microfluidic flow channel formed in a substrate and adapted to facilitate analysis or processing of the sample;
- generating a pressure pulse by changing a volume or pressure in a first reservoir operatively associated with the flow channel;
- and
- dampening or absorbing the pressure pulse using a second reservoir operatively associated with the flow channel.
1 more element
Dependencies are inferred from the claim text.