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US 2012/0015401 A1Published application
Plasmodium falciparum antigens and methods of use
AssigneesU.S.A as Represented by the Secretary of the Navy, Office of Naval Research (Code 00CC), Epimmune Inc.
InventorsAlessandro Sette, Denise L. Doolan, Daniel J. Carucci, John Sidney, Scott Southwood
Life of this patent
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Abstract
The subject invention provides novel Plasmodium falciparum antigens and novel polynucleotides encoding these antigens. Also provided by the subject invention are methods of using these antigens and polynucleotides.
Claims25
An isolated or purified polynucleotide:
- a) encoding a polypeptide comprising SEQ ID NO:
- 2;
- b) encoding a Human Leukocyte Antigen (HLA) binding fragment of SEQ ID NO:
- 2, said fragment comprising at least five consecutive amino acids of SEQ ID NO:
- 2;
- or
- c) that is complementary along the full length of said polynucleotide of a) or b).
4 more elements
A vector comprising a promoter operably linked to a polynucleotide:
- a) encoding a polypeptide comprising SEQ ID NO:
- 2;
- b) encoding a Human Leukocyte Antigen (HLA) binding fragment of SEQ ID NO:
- 2, said fragment comprising at least five consecutive amino acids of SEQ ID NO:
- 2;
- or
- c) that is complementary along the full length of said polynucleotide of a) or b).
4 more elements
An isolated transformed host cell comprising a polynucleotide:
- a) encoding a polypeptide comprising SEQ ID NO:
- 2;
- b) encoding a Human Leukocyte Antigen (HLA) binding fragment of SEQ ID NO:
- 2, said fragment comprising at least five consecutive amino acids of SEQ ID NO:
- 2;
- or
- c) that is complementary along the full length of said polynucleotide of a) or b).
4 more elements
Dependencies are inferred from the claim text.