Devices and method for accelerometer-based characterization of cardiac synchrony and dyssynchrony
AssigneeCardiosync, Inc.
InventorJohn Daniel Dobak, III
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Abstract
Systems and methods according to the invention employ an acceleration sensor to characterize the synchrony or dyssynchrony of the left ventricle. Patterns of acceleration related to myocardial contraction can be used to assess synchrony or dyssynchrony. Time-frequency transforms and coherence are derived from the acceleration. Information and numerical indices determined from the acceleration time frequency transforms and coherence can be used to find the optimal pacing location for cardiac resynchronization therapy. Similarly, the information can be used to optimize timing intervals including V to V and A to V timing.
Claims13
A method for measuring cardiac dyssynchrony, comprising:
- a. placing only one 3-axis acceleration sensor for disposition within a patient's coronary sinus;
- b. wherein said sensor is configured to measure a global acceleration of a left ventricle of a patient;
- c. and wherein said measured acceleration forms a pattern indicative of global dyssynchrony of the left ventricle.
A method for identifying an optimal pacing location, comprising:
- a. introducing an acceleration-measuring catheter into a coronary sinus of a patient;
- b. measuring a baseline pattern of left ventricular myocardial acceleration;
- c. placing a right ventricular pacing device in a right ventricle of the patient;
- d. placing a left ventricular pacing device in or on the left ventricle;
- e. moving the left ventricular pacing device to a plurality of locations in or on the left ventricle;
- f. performing biventricular or left ventricular pacing at the plurality of locations with the left ventricular pacing device;
- g. measuring an acceleration pattern with the biventricular or left ventricular pacing;
- h. determining a location of the left ventricle with a less dyssynchronous acceleration pattern;
- and
- i. selecting the less dyssynchronous location to implant a CRT pacing lead.
A method for improving the outcome of CRT, comprising:
- a. placing a catheter with an acceleration sensor in a coronary sinus of a patient;
- b. diagnosing a presence of dyssynchrony by measuring an acceleration pattern that characterizes dyssynchrony;
- c. inserting a pacing guide wire;
- d. test pacing with the pacing guide wire a plurality of locations in or on the left ventricle;
- e. identifying a location among the plurality having a less dyssynchronous acceleration pattern than other locations of the plurality;
- and
- f. implanting a left ventricular lead in said identified location.
Dependencies are inferred from the claim text.