Nanocomposite based biosensors and related methods
AssigneeIndian Institute of Technology Madras
InventorsSundara Ramaprabhu, Tessy Theres Baby
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Abstract
Disclosed are nanocomposite-based biosensors. The biosensors include an electrode, a nanocomposite over the surface of the electrode, the nanocomposite comprising a population of carbon nanotubes and a population of magnetic nanoparticles dispersed in the population of carbon nanotubes, wherein the magnetic nanoparticles comprise a ferromagnetic metal or compound thereof, and one or more biomolecules over the surface of the electrode, wherein the biomolecules are capable of undergoing a redox reaction with a target molecule. Also disclosed are nanocomposites, modified electrodes, kits, and methods for using the biosensors.
Claims20
A biosensor comprising:
- an electrode;
- a nanocomposite over the surface of the electrode, the nanocomposite comprising a population of carbon nanotubes and a population of magnetic nanoparticles dispersed in the population of carbon nanotubes, wherein the magnetic nanoparticles comprise a ferromagnetic metal or compound thereof;
- and
- one or more biomolecules over the surface of the electrode, wherein the biomolecules are capable of undergoing a redox reaction with a target molecule.
A method for determining a concentration of a target molecule in a sample, the method comprising:
- exposing the sample to a biosensor, the biosensor comprising an electrode;
- a nanocomposite over the surface of the electrode, the nanocomposite comprising a population of carbon nanotubes and a population of magnetic nanoparticles dispersed in the population of carbon nanotubes, wherein the magnetic nanoparticles comprise a ferromagnetic metal or compound thereof;
- and
- one or more biomolecules over the surface of the electrode, wherein the biomolecules are capable of undergoing a redox reaction with a target molecule, and
- detecting a signal from the biosensor, wherein the signal is correlated to the concentration of the target molecule in the sample.
A nanocomposite comprising:
- a population of carbon nanotubes;
- and
- a population of magnetic nanoparticles dispersed in the population of carbon nanotubes;
- wherein:
- the magnetic nanoparticles comprise core-shell magnetic nanoparticles;
- and
- the core comprises a ferromagnetic metal or a compound thereof.
Dependencies are inferred from the claim text.