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US 2011/0313513 A1Published application
Method and devices for preventing restenosis in cardiovascular stents
AssigneeMonarch Biosciences, Inc.
InventorAlfred David Johnson
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Abstract
Described herein are devices and methods fabricating devices having nanostructures that allow adhesion or growth of one cell type, such as endothelial cells, more than another cell type, such as smooth muscle cells. In particular, stent covers having such nanostructures are described, and methods for fabricating these stent covers. Also described herein are methods for optimizing the nanostructures forming the devices.
Claims8
A stent cover including nanostructures to which endothelial cells adhere preferentially compared to smooth muscle cells, the stent cover comprising:
- a thin-film of a shape memory material, the thin film at least partially surrounding
- a nanostructural surface, wherein the nanostructural surface comprises a layered nanoscale pattern having a shape and thickness that is selected so that endothelial cells preferentially adhere to the nanostructural surface as compared to smooth muscle cells.
Dependencies are inferred from the claim text.