Gastrointestinal anchor compliance

A method of treating a subject, comprising the steps of:

• securing a gastrointestinal implant device within a subject's intestine, the device including a flexible sleeve, open at both ends and adapted to extend into the subject's intestine;
• and a collapsible gastrointestinal anchor, coupled to a proximal portion of the sleeve and characterized by an average spring rate of about 13 Newtons/meter (N/m) or greater in a range of motion of about 20 mm or greater, the range of motion being within a diameter range defined by a relaxed diameter and a compressive elastic deformation diameter;
• and
• extending the distal end of the sleeve into the subject's intestine.

A collapsible gastrointestinal anchor comprising a wave spring having a plurality of barbs extending therefrom, the wave spring being characterized by:

• a relaxed diameter of about 40 millimeters (mm) or greater;
• a compressive elastic deformation diameter of about 12 mm or less;
• an average spring rate of about 13 Newtons/meter (N/m) or greater over a range of motion of about 20 mm or greater, the range of motion being within a diameter range defined by the relaxed diameter and the compressive elastic deformation diameter;
• and
• a radial force under compression, the radial force being about 0.1 Newtons (N) or greater at a diameter of 25 mm, and the radial force being about 0.1 N or greater over the range of motion,
• the spring rate and the radial force being measured while unloading the spring.

A gastrointestinal implant device comprising:

• a flexible sleeve, open at both ends and adapted to extend into a subject's intestine;
• and
• a collapsible gastrointestinal anchor coupled to a proximal portion of the sleeve, the anchor comprising a wave spring having a plurality of barbs extending therefrom,
• the wave spring being characterized by a relaxed diameter of about 40 millimeters (mm) or greater;
• a compressive elastic deformation diameter of about 12 mm or less;
• an average spring rate of about 13 Newtons/meter (N/m) or greater over a range of motion of about 20 mm or greater, the range of motion being within a diameter range defined by the relaxed diameter and the compressive elastic deformation diameter;
• and a radial force under compression, the radial force being about 0.1 Newtons (N) or greater at a diameter of 25 mm, and the radial force being about 0.1 N or greater over the range of motion,
• the spring rate and the radial forces being measured while unloading the spring.

A method of treating a subject, comprising the steps of:

• securing a gastrointestinal implant device within a subject's intestine, the device including a flexible sleeve, the sleeve open at both ends and adapted to extend into the subject's intestine, and a collapsible gastrointestinal anchor coupled to a proximal portion of the sleeve, the anchor comprising a wave spring having a plurality of barbs extending therefrom;
• and
• extending the distal end of the sleeve into the subject's intestine,
• the wave spring being characterized by a relaxed diameter of about 40 millimeters (mm) or greater;
• a compressive elastic deformation diameter of about 12 mm or less;
• an average spring rate of about 13 Newtons/meter (N/m) or greater over a range of motion of about 20 mm or greater, the range of motion being within a diameter range defined by the relaxed diameter and the compressive elastic deformation diameter;
• and a radial force under compression, the radial force being about 0.1 Newtons (N) or greater at a diameter of 25 mm, and the radial force being about 0.1 N or greater over the range of motion,
• the spring rate and the radial forces being measured while unloading the spring.