Use of BBI/BBIC for Treatment of Muscular Atrophy and Degenerative Muscle Disease
AssigneeThe Trustees of the University of Pennsylvania
InventorsH. Lee Sweeney, Carl A. Morris, Ann R. Kennedy
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Abstract
Methods for use of a composition comprising Bowman-Birk Inhibitor (BBI) or a derivative thereof in the treatment and/or prevention of skeletal muscle atrophy, to improve of skeletal muscle function, and to alleviate symptoms and/or slow progression of degenerative skeletal muscle diseases or disorders are provided.
Claims16
A method for reducing cycles of degeneration/regeneration of muscle fibers in a subject comprising administering to the subject a composition comprising a therapeutically effective amount of Bowman-Birk Inhibitor.
A method for increasing muscle mass, absolute force of a muscle, and/or cross-sectional area of muscle fibers, while maintaining specific muscle force in a subject comprising administering to the subject a composition comprising a therapeutically effective amount of Bowman-Birk Inhibitor.
A method for improving muscle strength in a subject comprising administering to the subject a composition comprising a therapeutically effective amount of Bowman-Birk Inhibitor.
Dependencies are inferred from the claim text.