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US 2011/0301066 A1Published application
Adhesion layer enhancement of plasmonic fluorescence
OwnerSteven M. Blairinventor
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Abstract
A light enhancement device includes at least two layers disposed over the substrate, including an adhesion layer disposed closer to the substrate than a metallic layer. At least one nanocavity extends into the metallic layer. The thickness of the adhesion layer and the diameter of the cavity have a ratio that is in the range of approximately 1:4 to 1:100. Capture molecules can be disposed within the nanocavities.
Claims27
A detection-enhancement device for biological assay, comprising:
- a) a substrate;
- b) a metallic layer disposed over the substrate;
- c) an array of multiple nanocavities extending into the metallic layer;
- d) the nanocavities each having a bottom and a sidewall laterally circumscribing each nanocavity;
- e) capture molecules disposed within the nanocavities;
- f) the metallic layer having a thickness between 50 to 200 nanometers, and the nanocavities having a lateral dimension of 65 to 190 nanometers;
- g) an adhesion layer adhering the metallic layer to the substrate;
- and
- h) a thickness of the adhesion layer and the diameter of the cavity having a ratio in the range of 1:4 to 1:100.
6 more elements
A light enhancement device comprising:
- a) a substrate;
- b) at least two layers disposed over the substrate, comprising at least a first layer and a second layer;
- c) the first layer is disposed closer to the substrate than the second layer;
- d) at least one nanocavity extending into the second layer;
- e) the first layer having a first layer thickness and a material, the second layer having a second layer thickness and a material, and the at least one cavity having a cavity diameter and a cavity shape adapted to enhance transmission of light through the at least one nanocavity;
- and
- f) the thickness of the first layer and the diameter of the cavity having a ratio that is in the range of approximately 1:4 to 1:100.
4 more elements
A light enhancement device comprising:
- a) a substrate;
- b) at least two layers disposed over the substrate, comprising at least a first layer and a second layer;
- c) the first layer is disposed closer to the substrate than the second layer;
- d) an array of multiple nanocavities extending into the second layer;
- e) the first layer having a first layer thickness and a material, the second layer having a second layer thickness and a material, the at least one cavity having a cavity diameter and a cavity shape adapted to enhance transmission of light through the at least one nanocavity;
- and
- f) the first layer causes an improvement in light transmission by a factor of at least 3.
4 more elements
A detection-enhancement device for biological assay, comprising:
- a) a substrate;
- b) a metallic layer disposed over the substrate;
- c) an array of multiple nanocavities extending into the metallic layer;
- d) the nanocavities each having a bottom and a sidewall laterally circumscribing each nanocavity;
- e) capture molecules disposed within the nanocavities;
- f) the metallic layer having a thickness between 50 to 200 nanometers, and the nanocavities having a lateral dimension of 65 to 190 nanometers;
- g) an adhesion layer adhering the metallic layer to the substrate;
- and
- h) a blocking layer disposed over the metallic layer including a material to resist light transmitting through the metallic layer.
6 more elements
Dependencies are inferred from the claim text.