A trigeminal nerve and extended trigeminal nervous system specific, topical anti-inflammatory and analgesic invention, which by a specific application, to areas which correlate to or relate to the various trigeminal branches and plexus, mitigates and acts to prevent migraine-type headache, cluster-type headache, tension-type headache, post-traumatic headache, atypical facial pain and cervical muscle spasm as well as other ideopathic head or facial pain or discomfort, associated with, or exacerbated by, inflammation but without the use of NSAIDS, glucocorticoid steroids or salicylites, said inflammation can be localized and corollary to the maxillary third molar apical area of the trigeminal nerve branches, system and plexus, or generally, in other areas correlated with or related to the intraoral and extraoral trigeminal nerve areas systems or plexus, where pain mitigation action is desirable, to which the invention is topically applied directly to any or all of the following, the gingival area of the mouth in the maxillary third molar apical area correlating to the plexus formed by the posterior superior alveolar branch of the ipsilateral maxillary nerve, the area of the inferior alveolar branch along the lower jaws outer gingival tissue between teeth and cheek encompassing about the area of the rearmost two molars and the wisdom tooth, the extraoral trigeminal nerve areas specified as follows, correlating with, or related to, the location of the, auriculotemporal nerve at the front base of the ear, temporomalar nerve at both jaw and temple, supratrocheal, lacrimal and supraorbital nerves of the forehead, buccal nerve of the cheek, mental nerve of the lower jaw, infratrochlear and nasal nerves along the nose, and infraorbital nerve of the cheek area adjacent the nose and under the eye, the invention is comprised of, in any of its forms, solid, powders, acids, oils, extracts, liquids, gels, sprays, any single or combination of anti-inflammatory herbs or botanicals (initially boswellia subsequently aloe) in any amount (initially to maximum solubility), and mixed into, by any means of combining these, a base vehicle which in this case, said base being comprised of, dimethyl sulfoxide, itself an anti-inflammatory and analgesic substance, in a liquid, gel, solid or semi-solid form, in any concentration between 0.01% and 99.99%, (initially 50% concentration), combined with water and urea or ethanol in any amount (initially water and urea), combined with or without any salts in any amount (initially 0.50%), such as NaCI or KCI, (initially NaCI), mixed by any method of mixing or combining with any, liquids, creams, acids, oils, emulsifiers, thickeners or stabilizers in any amount (initially carbopol subsequently xanthan gum and glycerol), with natural or artificial flavorings in any amount, (initially Mentha x piperita) , with natural or artificial sweeteners (initially stevia), in any amount, none of which are honey due to the risk of the spores of the bacterium clostridium botulinum which is often found in honey, with or without thickeners, solids or emulsifiers as needed in any amount (initially carbopol subsequently xanthan gum and glycerol), to create a liquid, gel, cream, powder, semi-solid or solid, allowing application to and adherence to gingival tissue, and generally, and to facilitate anti-inflammatory and analgesic action upon the tissues on, about, relating to, correlating with, or otherwise surrounding the afore-described areas which in any way relate to the trigeminal nerve and its branches, plexus or structures and is used to affix said anti-inflammatory composition, to, onto, into, beneath or through the gingival tissues and to said areas of inflammation by the normal solvent action of dimethyl sulfoxide, this topical application can be used as needed to mitigate acute symptoms, or as a prophylactic application, to manage chronic symptoms or mitigate the onset of acute symptoms and in order to manage chronic conditions, should the afore-described ingredients or components or any aspects of the invention, now or at some future time, be re-categorized by any government or law-making body, or be subject to any regulatory changes, this is envisioned by this claim and said claim would, therefore, survive any such regulatory changes, the invention considers any variation of the above described, to be inclusive to the invention, under the revisions and modifications statement included in this application, which states, it will be apparent to those well-acquainted in the art that revisions and modifications may be made without departing from my invention in its broader aspects, application or intent.