Functionalized Nano- and Micro-materials for Medical Therapies
AssigneesBattelle Memorial Institute, University of Washington through its Center for Commercialization
InventorsKarl Erik Hellstrom, Ingegerd Hellstrom, Pu Liu, Huafeng Wei, Jun Liu, Chenghong Lei, Baowei Chen, Xiaolin Li
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Abstract
Compositions containing an optionally surface-functionalized mesoporous support and a biologically active agent, and pharmaceutical compositions of the same, are provided herein. Such compositions can be useful in the treatment of tumors, for example, by injection of the composition at a location near the site of the tumor.
Claims20
A method for treating a tumor comprising inserting at a site near a tumor in a patient in need of treatment a therapeutically effective amount of a composition comprising
- (i) a mesoporous support having an optional surface functionalization, wherein the surface functionalization, when present, comprises functional groups capable of associating with the biologically active agent;
- and
- (ii) at least one biologically active agent, wherein at least a portion of each biologically active agent is contained within the pores of the mesoporous support.
A composition comprising (i) a mesoporous support having an optional surface functionalization, wherein the surface functionalization, when present, comprises functional groups capable of associating with a biologically active agent;
- and (ii) at least one biologically active agent, wherein at least a portion of each biologically active agent is contained within the pores of the mesoporous support.
Dependencies are inferred from the claim text.