Hpv types and variants associated with cervical cancer and the uses thereof
AssigneeDdl Diagnostics Laboratory B.V.
InventorsWilhelmus Gregorius Vincentius Quint, Maurits Nicolaas Cornelis De Koning, Daan Geraets, Leendert Jan Van Doorn, Silvia De Sanjose Llongueras, Francisco Javier Bosch
Life of this patent
Estimating the term…
Abstract
The invention relates to identification of novel sequences associated with cervical cancer, probes and kits for the identification of said sequences, and vaccines suitable for vaccination against new cancer causing HPV types.
Claims14
Use of a probe specific for one or more of HPV types 20, 61, 30, 67, 69 and 91, or a probe specific for the variants of HPV 64, 34, or 54 listed in table 1, in the screening of tissue samples for the identification of high risk HPV types.
A kit for identifying HPV high risk types associated with the development of cervical cancer, the kit comprising a means to specifically detect one or more of HPV types 20, 61, 30, 67, 69 and 91, or a means to specifically detect the variants of HPV 64, 34 or 54 listed in table 1.
Use of one or more of HPV types 20, 61, 30, 67 69 and 91, or use of the variants of HPV 64, 34, or 54 listed in table 1 in the preparation of a vaccine for prevention or treatment of HPV infection or disease.
A vaccine for the prevention of cervical cancer comprising an HPV antigen, or nucleic acid encoding said antigen, selected from HPV types 20, 61, 30, 67 69 and 91, or selected from the variants of HPV 64, 34, or 54 listed in table 1.
A probe specific for a high risk type HPV strain wherein the probe is specific to the detection of one of HPV types 20, 61, 30, 67, 69, 91, or the variants of HPV 64, 34, or 54 listed in table 1.
Dependencies are inferred from the claim text.