Vaccine Compositions for Inducing Immune Responses Against Components of Drusen
AssigneeNorthwestern University
InventorsArthur H. Neufeld, Ai Ling Wang
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Abstract
Disclosed are compositions and methods for treating or preventing the formation of drusen in a patient in need thereof. The compositions include an effective amount of at least one polypeptide present in drusen, or an immunogenic fragment or variant thereof that induces an immune response against the polypeptide, together with a pharmaceutical carrier, excipient, or diluent. The compositions are suitable as vaccines for treating or preventing drusen and diseases associated with drusen.
Claims20
A vaccine composition for treating or preventing drusen in a patient in need thereof, the composition comprising:
- (a) an effective amount of at least one polypeptide present in drusen or an immunogenic fragment or variant of the polypeptide, wherein the amount is effective for stimulating an immune response against the polypeptide after the vaccine composition is administered to the patient;
- and
- (b) a pharmaceutical carrier, excipient, or diluent.
Dependencies are inferred from the claim text.