Substituted isoxazole compounds
AssigneeThe Board of TRustees of the University of Illinoi University of Illinios
InventorsScott Hunter Watterson, Alaric J. Dyckman, William J. Pitts, Steven H. Spergel
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AssigneeThe Board of TRustees of the University of Illinoi University of Illinios
InventorsScott Hunter Watterson, Alaric J. Dyckman, William J. Pitts, Steven H. Spergel
Estimating the term…
Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein Q is R1 is alkyl or aryl, said aryl optionally substituted with one to five substituents independently selected from C1 to C6 alkyl, C1 to C4 haloalkyl, —OR4, and/or halogen; and R2, R3, R4, and n are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
A compound of Formula (I):
Dependencies are inferred from the claim text.