Antibody produced using ostrich and method for production thereof
AssigneesOsaka Prefecture University Public Corporation, Japan Science and Technology Agency
InventorYasuhiro Tsukamoto
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Abstract
Disclosed is an antibody produced using an ostrich. Also disclosed is a method for producing the antibody. By using an ostrich, it becomes possible to produce antibodies (particularly antibodies for medical use), which have been hardly produced by using the mammals such as the mouse and the rat, homogeneously in a single body, in large quantities and in a simple manner. The method can overcome a disadvantage of lot-to-lot variation which may occur in the production of polyclonal antibodies using other animals.
Claims3
A method of producing an ostrich antibody comprising the steps of:
- a. administering to an ostrich a human CD166 protein or a peptide fragment thereof as an antigen,
- b. producing an ostrich antibody against the protein or the peptide fragment thereof, where the ostrich antibody specifically binds to the protein or the peptide fragment thereof,
- c. isolating the ostrich antibody from an ostrich fluid, and
- d. producing a polyclonal or monoclonal antibody.
Dependencies are inferred from the claim text.