18f-labelled three-and four-carbon acids for pet imaging
AssigneeSloan-Kettering Institute for Cancer Research
InventorsNagavarakishore Pillarsetty, Steven Larson
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Abstract
Compositions containing three and four-carbon acids labeled with 18F at the 2-position and to their use for emission tomography are disclosed.
Claims24
A diagnostic composition comprising a pharmaceutical carrier for injection and a 2-[18F]-fluoro C3 or C4 acid.
(canceled)
-14. (canceled)
A method for detecting abnormalities in a tissue or organ of a mammal, said method comprising (1) administering to said mammal an amount of a 2-[18F]-C3 or C4 acid sufficient to be detected by a nuclear imaging technique (2) forming at least one image showing the distribution of the 2-[18F]-C3 or C4 acid within the tissue or organ of the mammal by nuclear imaging;
- and (3) detecting the abnormality by observing the image.
A method for rendering neoplastic tissue visible by positron emission tomography (PET) said method comprising delivering to said tissue an amount of a 2-[18F]-C3 or C4 acid sufficient to be detected by positron emission tomography.
Dependencies are inferred from the claim text.