Integrated Microfluidic Sensor System with Magnetostrictive Resonators
AssigneeKing Abdullah University of Science and Technology
InventorsCai Liang, Jurgen Kosel, Chinthaka Gooneratne
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Abstract
The present embodiments describe a method that integrates a magnetostrictive sensor with driving and detecting elements into a microfluidic chip to detect a chemical, biochemical or biomedical species. These embodiments may also measure the properties of a fluid such as viscosity, pH values. The whole system can be referred to lab-on-a-chip (LOC) or micro-total-analysis-systems (μTAS). In particular, this present embodiments include three units, including a microfluidics unit, a magnetostrictive sensor, and driving/detecting elements. An analyzer may also be provided to analyze an electrical signal associated with a feature of a target specimen.
Claims19
An apparatus comprising:
- a microfluidic device configured to prepare a target specimen for interaction with a magnetic sensor;
- a magnetic sensor coupled to the microfluidic device, the magnetic sensor configured to detect a feature of the target specimen;
- a driving element coupled to the magnetic sensor, the driving element configured to generate a driving signal for activating the magnetic sensor;
- and
- a sensing element coupled to the magnetic sensor, the sensing element configured to detect a response signal from the magnetic sensor in response to the driving signal, the response signal comprising information associated with the feature of the target specimen.
A system comprising:
- a microfluidic system comprising:
- a microfluidic device configured to prepare a target specimen for interaction with a magnetic sensor;
- a magnetic sensor coupled to the microfluidic device, the magnetic sensor configured to detect a feature of the target specimen;
- a driving element coupled to the magnetic sensor, the driving element configured to generate a driving signal for activating the magnetic sensor;
- and
- a sensing element coupled to the magnetic sensor, the sensing element configured to detect a response signal from the magnetic sensor in response to the driving signal, the response signal comprising information associated with the feature of the target specimen;
- and
- an analyzer coupled to the microfluidic system and configured to analyze the response signal to generate a quantitative representation of the feature of the target specimen.
A method comprising:
- preparing a target specimen, using a microfluidic device, for interaction with a magnetic sensor;
- interacting a feature of the target specimen with a magnetic sensor;
- generating a driving signal for activating the magnetic sensor;
- and
- detecting a response signal from the magnetic sensor in response to the driving signal, the response signal comprising information associated with the feature of the target specimen.
A method comprising:
- preparing a micro-volume of a target specimen;
- introducing the micro-volume of the target specimen to a magnetic sensor;
- activating the magnetic sensor with an driving signal;
- detecting a response signal from the magnetic sensor in response to the driving signal, the response signal comprising information associated with the feature of the target specimen.
Dependencies are inferred from the claim text.