Rice gene capable of imparting wide-spectrum disease resistance

A plant cell into which a DNA of any one of (a) to (d) below or a vector comprising the DNA has been introduced, wherein the plant cell can regenerate a plant which is resistant against either a pathogenic bacterium or a pathogenic fungus, or both:

• (a) a DNA encoding a protein comprising the amino acid sequence of SEQ ID NO:
• 2;
• (b) a DNA comprising the coding region of the nucleotide sequence of SEQ ID NO:
• 1;
• (c) a DNA encoding a protein comprising an amino acid sequence with one or more amino acid substitutions, deletions, additions, and/or insertions in the amino acid sequence of SEQ ID NO:
• 2;
• and
• (d) a DNA that hybridizes under stringent conditions with a DNA comprising the nucleotide sequence of SEQ ID NO:
• 1.

A method of screening for a candidate compound for a pharmaceutical agent which imparts to a plant resistance against either a pathogenic bacterium or a pathogenic fungus, or both, wherein the method comprises the steps of:

• (a) contacting a test compound with a cell or a cell extract comprising a DNA having a structure in which all or a part of the nucleotide sequence of SEQ ID NO:
• 3 is operably linked with a reporter gene;
• (b) measuring the expression level of the reporter gene;
• and
• (c) selecting a compound that increases the expression level compared to the expression level measured in the absence of the test compound.