Compositions and methods for re-programming cells without genetic modification
AssigneeVivoscript, Inc.
InventorsYong Zhu, Shili Wu, Jun Bao
Life of this patent
Estimating the term…
Abstract
The present inventions are directed to compositions and methods regarding the reprogramming of biological samples (such as cells) without introducing exogenous genes to the samples. In particular, the present inventions are directed to transducible materials that are capable of transducing into the biological samples but are not genes or causing genetic modifications. The present inventions also are directed to methods of reprogramming the path of biological samples or treating diseases using the tranducible compositions thereof.
Claims43
A transducible material comprising an effector domain.
A method of identify an effector domain comprising:
- covalently linking a test effector domain to a transduction domain to form a test transducible molecule;
- exposing the test molecule to a biological sample, and
- measuring a reprogramming level of the biological sample.
Dependencies are inferred from the claim text.