Methods and devices for injection of a substance into tissue
AssigneePalomar Medical Technologies, Inc.
InventorsGregory B. Altshuler, Ilya Yaroslavsky, David Tabatadze, Valery V. Tuchin, Andrei Belikov, Andrei Erofeev
Life of this patent
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Abstract
Substances are injected (e.g. laser injected) into skin tissue in order to change optical and/or mechanical properties of the tissue. Methods include ablating one or more micro-holes into tissue, pushing a substance into the one or more micro-holes with energy from the creation of the mirco-holes, with acoustic energy, and/or with laser energy. A container component is filled with the substance to be injected into the skin tissue.
Claims28
A method of driving a substance into a subject's skin, comprising:
- placing a substance in contact with or in proximity to a portion of the skin;
- applying energy to said skin portion so as to generate a plurality of micro-holes therein;
- and
- applying energy to at least a portion of said substance to generate pressure for forcing at least a portion of said substance into one or more of the plurality of micro-holes.
A method of driving a substance into a subject's skin, comprising:
- placing a container housing in contact with a portion of the skin, said container housing defining a compartment containing a substance therein, the container housing configured to seal the compartment between the skin and the container housing when the compartment is in contact with the skin;
- and
- applying ablative energy through at least a portion of the container housing thereby ablating said skin portion and so as to generate a plurality of micro-holes and such that a pressure within the compartment increases and drives at least a portion of said substance into said micro-holes with said increased pressure.
A container component for driving a substance into tissue, the component comprising:
- a compartment;
- a window, at least a portion of the window is optically transparent to laser energy, the window reflects at least a portion of the sonic energy created when the laser energy is applied to tissue and the window prevents escape of the reflected acoustic sonic energy from the compartment;
- and
- a wall, wherein at least a portion of the wall can form a seal with a tissue surface.
Dependencies are inferred from the claim text.