Patient-Specific Seizure Onset Detection System

A method of determining a focus of a patient's epileptic seizure, comprising:

• extracting at least a sample of at least one waveform monitoring neural activity in a selected brain portion of the patient,
• identifying an onset of an epileptic seizure of the patient by classifying at least one feature vector as belonging to a seizure or a non-seizure class, said classification being based on comparison of the feature vector with a measure derived from previously-obtained reference brain waveforms of the patient, and
• delivering a diagnostic agent to the patient upon detection of the onset of a seizure.

155-160. (canceled)

A system for delivering a diagnostic agent to a patient, comprising:

• a detector adapted to receive at least one waveform indicative of brain activity of a patient, said detector extracting at least a sample of said waveform and generating a feature vector corresponding to said sample,
• said detector comprising a classifier trained on previously-obtained reference waveforms of the patient, said classifier identifying a seizure onset by classifying said feature vector as belonging to a seizure class or a non-seizure class based on comparison with a measure derived from said previously-obtained reference waveforms of the patient, and
• a device for delivering a diagnostic agent to the patient in response to identification of a seizure onset.

A system for determining a focus of an epileptic seizure of a patient, comprising

• a device for monitoring at least one EEG waveform channel of the patient,
• a patient-specific seizure detector for detecting an onset of a seizure by classifying at least a feature vector derived from at least a sample of the waveform as belonging to a seizure or a non-seizure class, said detector performing the classification by comparing the feature vector with a measure computed based on one or more reference feature vectors previously derived for that patient, and
• a pump for delivering a radiotracer to the patient in response to detection of a seizure onset by said detector.

172-173. (canceled)