Method of producing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether
AssigneeZhejiang Lantian Environmental Protection Hi-Tech Co., Ltd.
InventorsWeiguo Xu, Hua LI
Life of this patent
Estimating the term…
Abstract
The present invention provides a preparation method of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether by reacting CH2FX with 1,1,1,3,3,3-hexafluoroisopropanol in the presence of acid-binding agent. The reaction can be also preformed in the presence of solvent and/or phase-transfer catalyst. The present method has the advantages of simple reaction, manageable control condition, high material conversion and product yield, and the product can be easily separated. The obtained fluoromethyl 1,1,1,3,3,3-hexafluoroisoprophyl ether can be used as a safe inhalation anesthetics.
Claims27
A preparation method of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether is characterized in that it allows reaction of compounds as specified in a general formula (1) with 1,1,1,3,3,3-hexafluoroisopropanol in the presence of acid-binding agent,
- CH2FX (1)
- wherein:
- X is either Cl, Br or I.
A preparation method of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether, wherein CH2FBr reacts with 1,1,1,3,3,3-hexafluoroisopropanol in the presence of acid-binding agent, solvent and phase-transfer catalyst.
Dependencies are inferred from the claim text.