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US 2011/0257267 A1Published application
Reducing the Risk of Pathological Effects of Traumatic Brain Injury
OwnerKevin Hadley, Terence Fealey +1inventors
InventorsKevin Hadley, Terence Fealey, Julian E. Bailes
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Abstract
The present disclosure provides methods and compositions for reducing the risk of pathological effects of traumatic brain injury.
Claims27
A method for reducing the risk of pathological effects of traumatic brain injury, comprising:
- (a) administering to a subject who is at risk of traumatic brain injury a composition comprising at least about 35 wt % docosahexaenoate (DHA), wherein the composition is administered in a prophylactically effective amount for a sufficient time period prior to engagement in an activity associated with a risk of traumatic brain injury to reduce the risk of pathological effects of traumatic brain injury, and wherein the composition has an eicosapentaenoate (EPA) content of less than about 2 wt % of the total fatty acid content.
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A method of protecting the brain of a human subject, the method comprising:
- administering to the subject, before an activity associated with a potential traumatic brain injuring event, an oral dosage form comprising at least 900 mg of DHA, wherein the dosage form comprises at least about 35 wt % docosahexaenoate (DHA) of the total fatty acid content, wherein the dosage form has an eicosapentaenoate (EPA) content of less than about 2 wt % of the total fatty acid content.
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Dependencies are inferred from the claim text.