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US 2011/0257221 A1Published application
Novel hydroxy-6-heteroarylphenanthridines and their use as pde4 inhibitors
AssigneeNYCOMED GmbH
InventorUlrich KAUTZ
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Abstract
Compounds of the formula Ia***** in which the substituents have the definitions provided in the specification, are novel, effective PDE4 inhibitors.
Claims16
1-30. (canceled)
A compound of formula Ia*****
- in which
- R1 is methoxy,
- R2 is methoxy, ethoxy, difluoromethoxy or 2,2-difluoroethoxy,
- R3 is hydrogen,
- R31 is hydrogen,
- R41 is hydrogen,
- R5 is hydrogen,
- Har is substituted by R6 and R7, and is pyridinyl, in which
- R6 is oxo, and
- R7 is methyl,
- or a salt of this compound.
8 more elements
Dependencies are inferred from the claim text.