Compounds for treatment of cancer

A compound represented by the structure of formula (Ia):

• A is substituted or unsubstituted single-, fused- or multiple-ring, aryl or (hetero)cyclic ring systems;
• substituted or unsubstituted, saturated or unsaturated N-heterocycles;
• substituted or unsubstituted, saturated or unsaturated S-heterocycles;
• substituted or unsubstituted, saturated or unsaturated O-heterocycles;
• substituted or unsubstituted, saturated or unsaturated cyclic hydrocarbons;
• or substituted or unsubstituted, saturated or unsaturated mixed heterocycles;
• B is
• R1, R2 and R3 are independently hydrogen, O-alkyl, O-haloalkyl, F, Cl, Br, I, CF3, CN, —CH2CN, NH2, hydroxyl, —(CH2)iNHCH3, —(CH2)iNH2, —(CH2)iN(CH3)2, —OC(O)CF3, C1-C5 linear or branched alkyl, haloalkyl, alkylamino, aminoalkyl, —OCH2Ph, —NHCO-alkyl, COOH, —C(O)Ph, C(O)O-alkyl, C(O)H, —C(O)NH2 or NO2;
• R10 and R11 are independently hydrogen, O-alkyl, O-haloalkyl, F, Cl, Br, I, CF3, CN, —CH2CN, NH2, hydroxyl, —(CH2)iNHCH3, —(CH2)iNH2, —(CH2)iN(CH3)2, —OC(O)CF3, C1-C5 linear or branched alkyl, haloalkyl, alkylamino, aminoalkyl, —OCH2Ph, —NHCO-alkyl, COOH, —C(O)Ph, C(O)O-alkyl, C(O)H, —C(O)NH2 or NO2;
• X is a bond, NH, C1 to C5 hydrocarbon, O, or S;
• Y is a bond, —C═O, —C═S, —C═N—NH2, —C═N—OH, —CH—OH, —C═CH—CN,
• C═N—CN, —CH═CH—, —C═C(CH3)2, —C═N—OMe, —(C═O)—NH, —NH—(C═O), —(C═O)—O, —O—(C═O), —(CH2)1-5—(C═O), (C═O)—(CH2)1-5, —(SO2)—, SO2, SO or S;
• wherein said A and B rings are optionally substituted by 1-5 substituents which are independently O-alkyl, O-haloalkyl, F, Cl, Br, I, CF3, CN, —CH2CN, NH2, hydroxyl, —(CH2)iNHCH3, —(CH2)iNH2, —(CH2)iN(CH3)2, —OC(O)CF3, C1-C5 linear or branched alkyl, haloalkyl, alkylamino, aminoalkyl, —OCH2Ph, —NHCO-alkyl, COOH, —C(O)Ph, C(O)O-alkyl, C(O)H, —C(O)NH2 or NO2;
• i is an integer between 0-5;
• l is an integer between 1-2;
• m is an integer between 1-3;
• and
• wherein if B is a benzene ring, a thiophene ring, a furan ring or an indole ring then X is not a bond or CH2 and A is not indole;
• if B is indole then X is not O;
• and
• if B is a thiazole ring then X is not a bond.