US 2011/0257158 A1Published application

Precompacted fast-disintegrating formulations of compounds with a low oral bioavailability

OwnerJan Peter Moschwitzer, Yu-San Wu +4inventors

InventorsJan Peter Moschwitzer, Yu-San Wu, Sophie Rolande Van Tomme, Henny Kuil, Aldo Vincent Ket, Lucia Maria Doesborgh-Dewit

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Abstract

This invention relates to the field of pharmaceutical chemistry. Embodiments of the present invention relate to, and provide precompacted fast-disintegrating formulations of compounds with a low oral bioavailability.

Claims14

Dependent claims

A solid pharmaceutical formulation for oral administration, comprising an active pharmaceutical ingredient, a hydroswelling polymer, and a precompacted granulate of a swellable excipient.

Dependencies are inferred from the claim text.

Facts

Application: 13/140,509Filed 17 Dec 2009
Priority: EP 08172247.219 Dec 2008
Published: 20 Oct 2011
Term ends: Not estimatedThe source records don’t support an estimate.

Classification6 codes

A61K 9/146
Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried,…: with…
A61K 9/2027
Organic macromolecular compounds: obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, polyacrylates
A61K 9/2077
Characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets;…: tablets…
A61P 43/00
Drugs for specific purposes, not provided for in groups a61p1/00-a61p41/00

Family

Application61/139,193Us provisional application · filed 19 Dec 2008
US 2011/0257158 A1This patent

From the US filing history. Foreign family members aren’t listed.

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