Formulation for oral transmucosal administration of lipid-lowering drugs
OwnerPhilippe Perovitch, Marc Mauryinventors
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Abstract
The invention relates to a formulation for delivering by oral transmucosal administration at least one lipid-lowering active principle, preferably from the statin family, said formulation including said active principle in the base or salt form, an aqueous alcohol solution titrating at least 30° alcohol, and optionally a pH correcting agent and/or an antioxidant, said active principle being in a stable and completely dissolved state in the aqueous alcohol solution. The invention also relates to a method of preparing said formulation and to the use thereof, preferably in single-dose packaging, for treating and preventing hyperlipemia and/or cardiovascular conditions.
Claims15
A formulation for oral transmucosal administration of at least one lipid-lowering drug and/or cardiovascular protection active principle, comprising:
- said lipid-lowering drug and/or cardiovascular protection active principle;
- an aqueous alcohol solution comprising water and ethanol titrating at least 30° alcohol, in which said active principle is present in a stable and completely dissolved state;
- and
- optionally, a pH corrector agent and/or an antioxidant.
Dependencies are inferred from the claim text.