Ultrasonic treatment chamber for preparing emulsions

A method for preparing an emulsion using an ultrasonic mixing system, the method comprising:

• introducing a first phase into a first inlet port of an elongate housing of a treatment chamber at a flow rate of from about 1 gram per minute to about 100,000 grams per minute;
• introducing a second phase into a second inlet port of the elongate housing of the treatment chamber at a flow rate of from about 1 gram per minute to about 100,000 grams per minute;
• ultrasonically activating the treatment chamber at a predetermined frequency with an elongate ultrasonic waveguide assembly extending longitudinally within the interior space of the housing to mix the first and second phases, the waveguide assembly comprising an elongate ultrasonic horn disposed at least in part intermediate the first and second inlet ports and an outlet port of the housing spaced longitudinally from the first and second inlet ports and having an outer surface located for contact with the first and second phases flowing within the housing from the first and second inlet ports to the outlet port, and a plurality of discrete agitating members in contact with and extending transversely outward from the outer surface of the horn intermediate the first and second inlet ports and the outlet port in longitudinally spaced relationship with each other, the agitating members and the horn being constructed and arranged for dynamic motion of the agitating members relative to the horn upon ultrasonic vibration of the horn at the predetermined frequency and to operate in an ultrasonic cavitation mode of the agitating members corresponding to the predetermined frequency.