Assay for troponin i using magnetic labels
AssigneeKoninklijke Philips Electronics N.V.
InventorsWendy Uyen Dittmer, Toon Hendrik Evers, Peggy De Kievit, Ricky Kamps, Joost Lambert Max Vissers, Michael Franciscus Wilhelmus Cornelis Martens, David Walterus Cornelis Dekkers
Life of this patent
Estimating the term…
Abstract
The present invention relates to a method for measuring Troponin I in a sample comprising the steps of providing a sample, contacting the sample with a monoclonal anti-Troponin I antibody coupled to a magnetic label, contacting the sample with a polyclonal anti-Troponin I antibody coupled to a sensor surface and detecting the magnetic label on the sensor surface. The invention further relates to a device and a cartridge for measuring Troponin I in a sample.
Claims14
Method for measuring Troponin I in a sample comprising at least the following steps:
- a. Providing a sample
- b. Contacting the sample with a monoclonal anti-Troponin I antibody coupled to a magnetic label
- c. Contacting the sample with a polyclonal anti-Troponin I antibody coupled to a sensor surface, or at least two different anti-Troponin I antibodies coupled to a sensor surface
- d. Detecting the magnetic label on the sensor surface, wherein steps b and c can be performed in any order.
A cartridge for use in an assay device, comprising:
- a. a monoclonal anti-Troponin I antibody bound to a magnetic label
- b. a polyclonal anti-Troponin I antibody coupled to a sensor surface, or at least two different anti-Troponin I antibodies coupled to a sensor surface, within the cartridge, and
- c. a sample inlet.
Dependencies are inferred from the claim text.