Methods and compositions for the detection of ovarian cancer
AssigneeUniversity Health Network
InventorsEleftherios P. Diamandis, Cynthia Kuk
Life of this patent
Estimating the term…
Abstract
Provided is a method of screening for, diagnosing or detecting ovarian cancer in a subject comprising (a) determining a level of mdogen-2 in a test sample from the subject, and (b) comparing the level of mdogen-2 in the test sample with a control, where detecting an increase in the level of mdogen-2 in the test sample compared to the control is indicative of ovarian cancer in the subject.
Claims40
A method of screening for, diagnosing or detecting ovarian cancer or an increased likelihood of developing ovarian cancer in a subject comprising:
- (a) determining a level of a biomarker in a test sample from the subject wherein the biomarker is selected from the biomarkers set out in Table 2;
- and
- (b) comparing the level of the biomarker in the test sample with a control;
- wherein detecting an increased level of the biomarker in the test sample compared to the control is indicative the subject has ovarian cancer or an increased likelihood of developing ovarian cancer.
3-6. (canceled)
(canceled)
13-15. (canceled)
(canceled)
(canceled)
24-33. (canceled)
(canceled)
37-42. (canceled)
44-46. (canceled)
49-50. (canceled)
52-55. (canceled)
A composition comprising two or more detection agents, wherein at least one detection agent detects a biomarker selected from the biomarkers set out in Table 2, and wherein a second detection agent detect a biomarker selected from Table 2, Table 1 and CA125, wherein the composition is used to measure the level of at least two biomarkers.
57-59. (canceled)
62-63. (canceled)
A kit comprising at least two detection agents, wherein at least one detection agent detects a biomarker selected from the biomarkers set out in Table 2;
- and instructions for use;
- wherein the detection agents are used to measure the level of two biomarkers.
66-67. (canceled)
(canceled)
Dependencies are inferred from the claim text.