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US 2011/0256543 A1Published application
Use of novel cytokine receptors as biomarkers and therapeutic targets in human cancer
AssigneeDuke University
InventorsMurat O. Arcasoy, Zishan A. Haroon
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Abstract
Nucleic acids encoding erythropoietin isoforms are described herein, as well as the encoded isoforms, methods of detecting the same, and methods of screening for and treating cancer.
Claims24
An isolated nucleic acid selected from the group consisting of
- a nucleic acid encoding erythropoietin receptor isoform 1 and having the sequence given herein as SEQ ID NO:
- 4;
- a nucleic acid encoding erythropoietin receptor isoform 2 and having the sequence given herein as SEQ ID NO:
- 6;
- a nucleic acid encoding erythropoietin receptor isoform 3 and having the sequence given herein as SEQ ID NO:
- 8;
- a nucleic acid encoding erythropoietin receptor isoform 4 and having the sequence given herein as SEQ ID NO:
- 10;
- a nucleic acid encoding erythropoietin receptor isoform 5 and having the sequence given herein as SEQ ID NO:
- 12;
- a nucleic acid that encodes the opposite strand of a nucleic acid as set forth above.
8 more elements
Dependencies are inferred from the claim text.