Compositions and methods for purifying and crystallizing molecules of interest

The composition-of-matter of claim 6, wherein said antibody binding moiety comprise an antibody or an antibody fragment.

A composition-of-matter comprising at least one ligand capable of binding a target molecule or cell of interest, said at least one ligand being a composite ligand which comprises a scaffold moiety attached to at least one target recognition moiety capable of directly or indirectly binding the target molecule, cell or virus, said at least one ligand being attached to at least two coordinating moieties selected capable of directing the composition-of-matter to form a non-covalent complex when co-incubated with a coordinator ion or molecule.

A composition-of-matter comprising at least one ligand capable of binding a His-tagged molecule, said at least one ligand being a composite ligand which comprises an scaffold moiety attached to at least one chelator molecule capable of indirectly binding the His-Tagged molecule via a metal ion, said at least one ligand being attached to at least two coordinating moieties selected capable of directing the composition-of-matter to form a non-covalent complex when co-incubated with a coordinator ion or molecule.