Enhancement of the Anti-Leukemic Effect of Thalidomide
OwnerErian Girgis, Magdi Solimaninventors
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Abstract
The cytotoxic effects of thalidomide are enhanced when it is used in combination with other chemotherapeutic agents, particularly arsenic trioxide, indicating benefits for the treatment of blood-related cancers, especially acute myelogenous leukemia.
Claims18
A pharmaceutical composition having anti-cancer activity comprising thalidomide, an arsenical compound, and a pharmaceutical carrier.
A pharmaceutical composition adapted for oral administration, comprising thalidomide, an arsenical compound, and a pharmaceutical carrier.
A method of treating a patient with cancer comprising administering to the individual a composition comprising therapeutically effective amounts of thalidomide and an arsenical compound.
Dependencies are inferred from the claim text.