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US 2011/0256226 A1Published application
Opioid agonist formulations with releasable and sequestered antagonist
AssigneePurdue Pharma L.P.
InventorsChristopher Breder, Curtis Wright, Benjamin Oshlack
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Abstract
Disclosed are oral dosage forms, comprising (i) a therapeutically effective amount of an opioid agonist; (ii) an opioid antagonist in releasable form; and (iii) a sequestered opioid antagonist which is not released when the dosage form is administered intact, and methods thereof.
Claims27
An oral dosage form comprising:
- (i) a therapeutically effective amount of an opioid agonist;
- (ii) an opioid antagonist in releasable form;
- and
- (iii) a sequestered opioid antagonist which is not released when the dosage form is administered intact.
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