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US 2011/0256222 A1Published application
Recombinant Protein Enriched in a Heparin Binding Site and/or in a Heparan Sulfate Binding Site
OwnerArjo Lysander De Boer, Jan Bastiaan Bouwstrainventors
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Abstract
The invention relates to a recombinant protein enriched in a heparin binding site and/or a heparan sulfate binding site. Such recombinant protein is used as an in vivo controlled release system of a protein of interest.
Claims17
-12. (canceled)
A recombinant gelatin-like protein essentially free of hydroxyproline residues enriched in a heparin binding site and/or a heparan sulfate binding site, wherein the heparin binding site and/or a heparan sulfate binding site is selected from the group consisting of:
- GBBGB (SEQ ID NO:
- 11), GLPGMKGHRGFS (SEQ ID NO:
- 12), GRKGR (SEQ ID NO:
- 13), GKRGK (SEQ ID NO:
- 17) and KEDK (SEQ ID NO:
- 14), wherein B is a basic amino acid.
3 more elements
Dependencies are inferred from the claim text.