Hydrolyzed hydrogels
AssigneeCambridge Polymer Group, Inc.
InventorsEdward T. Kopesky, Jason A. Berlin, Martin F. Van Buren, Gavin J.C. Braithwaite
Life of this patent
Estimating the term…
Abstract
The invention provides methods of making hydrolyzed cross-linked polyvinyl alcohol (PVA) hydrogels by polymerizing vinyl acetate (VAc) monomers to polyvinyl acetate (PVAc) polymer network by chemical-crosslinking and hydrolysis. The invention also provides methods for including pendant chains in the hydrogel during the polymerization process. Materials produced and use of the cross-linked hydrolyzed PVA hydrogels also are disclosed herein.
Claims21
1-65. (canceled)
A method for making a hydrolyzed cross-linked hydrogel comprising the steps of:
- (a) polymerizing a monomer in the presence of a crosslinking agent and one or more molecules, thereby producing a crosslinked polymer network containing pendant chains;
- (b) hydrolyzing the crosslinked polymer network, thereby forming a hydrogel having hydrophilic polymer network;
- and
- (c) hydrating the polymer network, thereby forming a hydrolyzed cross-linked hydrogel having a hydrophilic network and pendant chains.
A method of making a hydrolyzed cross-linked polyvinyl alcohol) (PVA)-hydrogel, wherein the method comprises the steps of:
- (a) polymerizing vinyl acetate (VAc) monomers in the presence of a crosslinking agent and one or more molecules, thereby producing a crosslinked poly(vinyl acetate) (PVAc) polymer network containing pendant chains;
- (b) hydrolyzing the crosslinked PVAc polymer network, thereby forming a hydrogel having hydrophilic PVAc polymer network;
- and
- (c) hydrating the PVAc polymer network, thereby forming a hydrolyzed cross-linked hydrogel having a hydrophilic PVAc polymer network and pendant chains.
A hydrolyzed cross-linked polyvinyl alcohol) (PVA)-hydrogel made by a method comprising the steps of.
- (a) polymerizing vinyl acetate (VAc) monomers in the presence of a crosslinking agent and one or more molecules, thereby producing a crosslinked poly(vinyl acetate) (PVAc) polymer network containing pendant chains;
- (b) hydrolyzing the crosslinked PVAc polymer network, thereby forming a hydrogel having hydrophilic PVAc polymer network;
- and
- (c) hydrating the PVAc polymer network, thereby forming a hydrolyzed cross-linked hydrogel having a hydrophilic PVAc polymer network and pendant chains.
Dependencies are inferred from the claim text.