Antibody formulation
AssigneeMedImmune, LLC
InventorsSteven Bishop, Jenny S. Wolford
Life of this patent
Estimating the term…
Abstract
The present invention provides high concentration liquid formulations of antibodies or fragments thereof that specifically bind to a human interferon alpha polypeptide The formulation provides for an anti-13H5 anti-human interferon alpha antibody A pre-filled syringe containing the formulation is also disclosed.
Claims21
A pre-filled syringe containing a sterile, stable aqueous formulation comprising a 13H5 anti-human interferon alpha antibody, histidine, trehalose and polysorbate 80.
A method of preparing a pre-filled syringe containing a sterile, stable aqueous formulation comprising a 13H5 anti-human interferon alpha antibody, comprising:
- a) admixing a solution comprising a 13H5 anti-human interferon alpha antibody with at least one excipient selected from the group consisting of:
- a buffering agent, salt, carbohydrate and surfactant;
- and
- b) loading the solution comprising a 13H5 anti-human interferon alpha antibody and at least one excipient into a syringe.
Dependencies are inferred from the claim text.