Monoclonal Antibodies Specific to the Fusion Peptide From Hemagglutinin From Influenza A Viruses and Uses Thereof

Monoclonal antibody 1C9 as produced by hybridoma 1C9 which is deposited with the American Type Culture Collection with Accession Number PTA-8759.

A method for detecting an influenza A virus in a biological specimen which comprises contacting the specimen with a first binding protein that binds specifically to an epitope of a glycoprotein of influenza A virus, said first binding protein having substantially the immunological binding characteristics of monoclonal antibody 1C9.

A kit for detecting an influenza A virus in a biological specimen which comprises a first binding protein that binds specifically to an epitope of a glycoprotein of an influenza A virus, said first binding protein having substantially the immunological binding characteristics of monoclonal antibody 1C9 together with reagents for the detection of binding of said binding protein to said envelope glycoprotein.

A method of treating a subject infected with an influenza A virus which comprises administering to said subject a therapeutically effective amount of a binding protein that binds specifically to an epitope of a glycoprotein of an influenza A virus that has substantially the immunological binding characteristics of monoclonal antibody 1C9.

A method of protecting a subject from an influenza A virus infection comprising administering to said subject a binding protein that binds specifically to an epitope of a glycoprotein of an influenza A virus that has substantially the immunological binding characteristics of monoclonal antibody 1C9 in an amount effective to protect the subject from influenza A virus infection.