Myostatin binding proteins

An antigen binding protein which specifically binds to myostatin and comprises CDRH3 of SEQ ID NO:

• 3;
• or a variant CDRH3 wherein the variant CDRH3 is (i) any one of SEQ ID NOs:
• 82-92, or 110;
• or (ii) is SEQ ID NO:
• 3 with any one of the following Kabat substitutions V102Y, V102H, V102I, V102S, V102D or V102G.

An antigen binding protein which specifically binds to myostatin and comprises:

• (i) a heavy chain variable region selected from SEQ ID NO:
• 7 or SEQ ID NO:
• 25;
• and/or a light chain variable region selected from SEQ ID NO:
• 8 or SEQ ID NO:
• 21;
• or a variant heavy chain variable region or light chain variable region with 90% or greater sequence identity to the heavy chain variable region of SEQ ID NO's:
• 7 or 25 or light chain variable region of SEQ ID NO's:
• 8 or 21.
• (ii) a heavy chain of SEQ ID NO:
• 26;
• and/or a light chain selected from SEQ ID NO:
• 27 or SEQ ID NO:
• 37;
• or a variant heavy chain variable region or light chain variable region with 90% or greater sequence identity to the heavy chain variable region of SEQ ID NO:
• 26 or light chain variable region of SEQ ID NO's:
• 27 or 37.