Contrast media compositions

Contrast media compositions comprising iodine containing contrast enhancing compounds wherein

• one or more compounds are of formula (I)
• and salts or optical active isomers thereof,
• wherein each of R1, R2 and R3 are the same or different and denotes a hydrogen atom or a non-ionic hydrophilic moiety, provided that at least one of the R1, R2 and R3 groups in the compound of formula (I) is a hydrophilic moiety,
• and;
• one or more compounds are of formula (II)
• Formula (II)
• R—N(CHO)—X—N(R6)—R (II)
• and salts or optical active isomers thereof,
• wherein
• X denotes a C3 to C8 straight or branched alkylene moiety optionally with one or two CH2 moieties replaced by oxygen atoms, sulphur atoms or NR4 groups and wherein the alkylene moiety optionally is substituted by up to six —OR4 groups;
• R4 denotes a hydrogen or a C1 to C4 straight or branched alkyl group;
• R6 denotes a hydrogen atom or an acyl function;
• and
• each R independently is the same or different and denotes a triiodinated phenyl group further substituted by two groups R5 wherein each R5 is the same or different and denotes a hydrogen atom or a non-ionic hydrophilic moiety, provided that at least one R5 group in the compound of formula (II) is a hydrophilic moiety.