Sustained release delivery devices
AssigneepSivida US, Inc.
InventorPaul Ashton
Life of this patent
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AssigneepSivida US, Inc.
InventorPaul Ashton
Estimating the term…
An injectable drug delivery device includes a core containing one or more drugs and one or more polymers. The core may be surrounded by one or more polymer outer layers (referred to herein as “coatings,” “skins,” or “outer layers”). In certain embodiments, the device is formed by extruding or otherwise preforming a polymeric skin for a drug core. The drug core may be co-extruded with the skin, or inserted into the skin after the skin has been extruded, and possibly cured. In other embodiments, the drug core may be coated with one or more polymer coatings. These techniques may be usefully applied to fabricate devices having a wide array of drug formulations and skins that can be selected to control the release rate profile and various other properties of the drugs in the drug core in a form suitable for injection using standard or non-standard gauge needles.
A drug delivery device shaped and sized for injection comprising:
A drug delivery device comprising:
A method for treating an eye disease or disorder with fewer side effects, comprising administering a drug to an eye of a patient in need thereof daily for a period of at least 3 months, wherein said drug is administered at a release rate of less than or equal to 0.4 μg/day to treat said disease or disorder without causing a significant increase in IOP in a substantial percentage of treated patients.
A method for decreasing excess foveal thickness in a patient in need thereof, comprising administering a drug to an eye of said patient for a period of at least 3 months, wherein said drug is administered at a release rate of less than or equal to 0.4 μg/day to decrease excess foveal thickness.
Dependencies are inferred from the claim text.