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US 2011/0237970 A1Published application
Determining elastance and resistance
AssigneeKoninklijke Philips Electronics N.V.
InventorFernando Jose Isaza
Life of this patent
Estimating the term…
Abstract
The elastance and a resistance of a subject being ventilated are determined. The determination of elastance and resistance of the breathing of the subject is made without adjusting the ventilation of the subject to facilitate the determination. That is, the determination of elastance and resistance of the subject is made without manipulating one or more parameters of the ventilation in a manner not dictated by a treatment algorithm that is designed to ventilate the subject effectively and/or comfortably.
Claims48
A system configured to determine an elastance and a resistance of the breathing of a subject, the system comprising:
- a circuit in communication with an airway of a subject to deliver gas to the airway of the subject and to receive gas from the airway such that the subject is mechanically ventilated by the gas delivered to and received from the airway via the circuit;
- a sensor configured to generate a output signal that conveys information related to a parameter of gas at or near the airway;
- and
- a processor configured to determine an elastance and a resistance of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein the processor is configured to determine the elastance and the resistance of the breathing of the subject by (i) determining parameters of gas at or near the airway of the subject at two or more separate points in time at which muscle pressure of the subject is at or near zero based on the output signal, and (ii) determining the elastance and the resistance of the breathing of the subject based on the determined parameters of the gas at or near the airway of the subject at the two or more separate points in time at which the muscle pressure of the subject is at or near zero, and wherein the elastance and the resistance are determined by functions that describe the values of elastance and resistance as a function of the determined parameters of the gas at or near the airway at the two or more separate points in time at which the muscle pressure of the subject is at or near zero.
1 more element
A method of determining an elastance and a resistance of the breathing of a subject, the method comprising:
- (a) delivering gas to and receiving gas from an airway of a subject to mechanically ventilate the subject;
- (b) generating an output signal that conveys information related to a parameter of the gas being delivered to or received from the airway of the subject;
- and
- (c) determining an elastance and a resistance of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein determining the elastance and the resistance comprises:
- (1) determining parameters of gas at or near the airway at two or more separate points in time at which the muscle pressure of the subject is at or near zero based on the output signal, and
- (2) determining the elastance and the resistance based on the determined parameters of the gas at or near the airway at the two or more separate points in time at which the muscle pressure of the subject is at or near zero, and wherein the elastance and resistance are determined by functions that describe the values of elastance and resistance as a function of the determined parameters of the gas at or near the airway at the two or more separate points in time at which the muscle pressure of the subject is at or near zero.
3 more elements
A system configured to determine an elastance and a resistance of the breathing of a subject, the system comprising:
- (a) means for delivering gas to and receiving gas from an airway of a subject to mechanically ventilate the subject;
- (b) means for generating an output signal that conveys information related to a parameter of the gas being delivered to or received from the airway of the subject;
- and
- (c) means for determining an elastance and a resistance of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein the means for determining the elastance and the resistance comprises:
- (1) means for determining parameters of gas at or near the airway of the subject at two or more separate points in time at which the muscle pressure of the subject is at or near zero based on the output signal, and
- (2) means for determining the elastance and the resistance of the subject based on the determined parameters of the gas at or near the airway of the subject at the two or more separate points in time at which the muscle pressure of the subject is at or near zero, and wherein the elastance and resistance of the breathing of the subject are determined by functions that describe the values of elastance and resistance as a function of the determined parameters of the gas at or near the airway of the subject at the two or more separate points in time at which the muscle pressure of the subject is at or near zero.
3 more elements
A system configured to determine an elastance and a resistance of the breathing of a subject, the system comprising:
- a circuit in communication with an airway of a subject to deliver gas to the airway of the subject and to receive gas from the airway of the subject such that the subject is mechanically ventilated by the gas delivered to and received from the airway via the circuit;
- a sensor configured to generate an output signal that conveys information related to a parameter of gas at or near the airway of the subject;
- and
- a processor configured to determine an elastance and a resistance of the breathing of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein the processor is configured to determine the elastance and the resistance of the breathing of the subject by (i) determining parameters of gas at or near the airway of the subject at a detection point in time at which muscle pressure of the subject and the time derivative of muscle pressure of the subject are at or near zero based on the output signal, and (ii) determining the elastance and the resistance of the subject from functions that describe the values of elastance and resistance as a function of the determined parameters of the gas at or near the airway at the detection point in time, and wherein the functions implemented to determine the values of elastance and resistance correspond to a system of equations in which elastance and resistance are unknown parameters, muscle pressure is assumed to be zero, and the time derivative of muscle pressure is assumed to be zero.
1 more element
A method of determining an elastance and a resistance of the breathing of a subject, the method comprising:
- (a) delivering gas to and receiving gas from an airway of a subject to mechanically ventilate the subject;
- (b) generating an output signal that conveys information related to a parameter of the gas being delivered to or received from the airway;
- and
- (c) determining an elastance and a resistance of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein determining the elastance and the resistance of the breathing of the subject comprises:
- (1) determining parameters of gas at or near the airway at a detection point in time at which the muscle pressure of the subject and the time derivative of muscle pressure of the subject are at or near zero based on the output signal, and
- (2) determining the elastance and the resistance from functions that describe the values of elastance and resistance as a function of the determined parameters of the gas at or near the airway of the subject at the detection point in time, and wherein the functions implemented to determine the values of elastance and resistance correspond to a system of equations in which elastance and resistance are unknown parameters, muscle pressure is assumed to be zero, and the time derivative of muscle pressure is assumed to be zero.
3 more elements
A system configured to determine an elastance and a resistance of the breathing of a subject, the system comprising:
- (a) means for delivering gas to and receiving gas from an airway of a subject to mechanically ventilate the subject;
- (b) means for generating an output signal that conveys information related to a parameter of the gas being delivered to or received from the airway of the subject;
- and
- (c) means for determining an elastance and a resistance of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein the means for determining the elastance and the resistance of the breathing of the subject comprises:
- (1) means for determining parameters of gas at or near the airway at a detection point in time at which the muscle pressure of the subject and the time derivative of muscle pressure of the subject are at or near zero based on the output signal, and
- (2) means for determining the elastance and the resistance from functions that describe the values of elastance and resistance as a function of the determined parameters of the gas at or near the airway of the subject at the detection point in time, and wherein the functions implemented to determine the values of elastance and resistance correspond to a system of equations in which elastance and resistance are unknown parameters, muscle pressure is assumed to be zero, and the time derivative of muscle pressure is assumed to be zero.
3 more elements
A system configured to determine an elastance of the breathing of a subject, the system comprising:
- a circuit in communication with an airway of a subject to deliver gas to the airway of the subject and to receive gas from the airway of the subject such that the subject is mechanically ventilated by the gas delivered to and received from the airway via the circuit;
- a sensor configured to generate an output signal that conveys information related to a parameter of gas at or near the airway of the subject;
- and
- a processor configured to determine an elastance of the breathing of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein the processor is configured to determine the elastance of the breathing of the subject by (i) determining parameters of gas, including flow rate, at or near the airway of the subject based on the output signal, (ii) identifying, from the determined parameters of gas at or near the airway of the subject, a point in time at which the subject is exhaling and the flow rate of the gas reaches an extrema, and (iii) determining the elastance of the breathing of the subject based on the parameters of gas at or near the airway of the subject at the identified point in time.
1 more element
A method of determining an elastance and a resistance of the breathing of a subject, the method comprising:
- (a) delivering gas to and receiving gas from an airway of a subject to mechanically ventilate the subject;
- (b) generating an output signal that conveys information related to a parameter of the gas being delivered to or received from the airway of the subject;
- and
- (c) determining an elastance of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein determining the elastance of the breathing of the subject comprises:
- (1) determining parameters of gas, including flow rate, at or near the airway of the subject based on the output signal,
- (2) identifying, from the determined parameters of gas at or near the airway of the subject, a point in time at which the subject is exhaling and the flow rate of the gas reaches an extrema, and
- (d) determining the elastance of the subject from based on the determined parameters of the gas at or near the airway of the subject at the identified point in time.
4 more elements
A system configured to determine an elastance and a resistance of the breathing of a subject, the system comprising:
- (a) means for delivering gas to and receiving gas from an airway of a subject to mechanically ventilate the subject;
- (b) means for generating an output signal that conveys information related to a parameter of the gas being delivered to or received from the airway of the subject;
- and
- (c) means for determining an elastance of the subject without the ventilation of the subject being adjusted to facilitate the determination, wherein determining the elastance of the breathing of the subject comprises:
- (1) means for determining parameters of gas, including flow rate, at or near the airway of the subject based on the output signal,
- (2) means for identifying, from the determined parameters of gas at or near the airway of the subject, a point in time at which the subject is exhaling and the flow rate of the gas reaches an extrema, and
- (3) means for determining the elastance of the breathing of the subject from based on the determined parameters of the gas at or near the airway of the subject at the identified point in time.
4 more elements
Dependencies are inferred from the claim text.